Vierhapper H, Bratusch-Marrain P, Waldhäusl W
J Clin Endocrinol Metab. 1980 Jun;50(6):1131-4. doi: 10.1210/jcem-50-6-1131.
The arginine-induced release of insulin, glucagon, GH, and PRL was studied in eight normal male volunteers. Pretreatment with indomethacin (150 mg for 3 days) failed to modify the effect of arginine on the release of these hormones. As both indomethacin and acetylsalicylic acid are potent inhibitors of the endogenous prostaglandin synthesis, these results indicate that the effect of acetylsalicylic acid on insulin and glucagon secretion, as described by others, seems to be unrelated to the suppression of endogenous prostaglandin synthesis.
在八名正常男性志愿者中研究了精氨酸诱导的胰岛素、胰高血糖素、生长激素和催乳素的释放情况。用吲哚美辛（150毫克，持续3天）预处理未能改变精氨酸对这些激素释放的影响。由于吲哚美辛和乙酰水杨酸都是内源性前列腺素合成的强效抑制剂，这些结果表明，如其他人所描述的，乙酰水杨酸对胰岛素和胰高血糖素分泌的影响似乎与内源性前列腺素合成的抑制无关。
