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Recessive male-determining genes.

作者信息

Wachtel S S, Basrur P, Koo G C

出版信息

Cell. 1978 Sep;15(1):279-81. doi: 10.1016/0092-8674(78)90103-4.

Abstract

The autosomal dominant gene polled (P) causes hornlessness in goats. Chromosomal females (XX) that are P/P homozygotes develop testes or ovotestes. Thus with respect to its testis-determining properties, P or a closely linked gene acts as an autosomal recessive. Polled intersex goats are H-Y+. This finding is consistent with the view that there may be a cluster of testis-determining H-Y genes on the Y chromosome, and that translocation of a subcritical portion of these genes may generate a recessive mode of sex determination.

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