Burkhardt F, Schilt U, Saner H
Schweiz Med Wochenschr. 1980 Apr 12;110(15):555-62.
During a minor rubella epidemic in a Swiss army recruit training camp (Spring 1978), recent rubella infection was proved in 20 out of 22 investigated cases. In 18 cases virus replication could be shown by means of indirect immunofluorescence (IIF). Due to its higher sensitivity and easier performance in comparison with conventional echo interference, we believe IIF should be the method of choice for rubella virus isolation. In 2 out of 22 cases, the possibility of a secondary infection was discussed. A chceklist is given showing the necessary steps for virological investigations we think should be carried out to define immunity status, confirm or rule out a rubella infection, particular weight being attached to the embryopathy question. This article is therefore intended to provide the clinician interested in virological problems with a total to enable him to take the necessary measures for detection of rubella infection and interpretation of laboratory findings.
在瑞士陆军新兵训练营发生的一次小规模风疹疫情期间（1978年春季），在22例受调查病例中，有20例被证实近期感染了风疹。18例病例中通过间接免疫荧光法（IIF）显示有病毒复制。与传统的回声干扰法相比，由于其更高的敏感性和更易操作，我们认为IIF应是风疹病毒分离的首选方法。在22例病例中有2例讨论了二次感染的可能性。给出了一份检查清单，列出了我们认为为确定免疫状态、确认或排除风疹感染而应进行的病毒学调查的必要步骤，特别强调了胚胎病问题。因此，本文旨在为对病毒学问题感兴趣的临床医生提供全面信息，使他能够采取必要措施检测风疹感染并解释实验室结果。
