Stolinsky D C
West J Med. 1980 Mar;132(3):189-208.
Neoplasms can produce a variety of remote effects on the host; these are referred to as paraneoplastic syndromes. The syndromes may affect any of the systems of the body, may precede or follow the diagnosis of the underlying neoplasm, and may or may not parallel the course of the neoplasm in severity. The diagnosis of and therapy for these syndromes can be challenging to a physician, but successful therapy may bring about worthwhile relief for the patient. In addition, the syndromes and the substances that cause them are sometimes useful in diagnosing and in following the course of certain neoplasms. Perhaps of greater importance, study of these remote effects of neoplasia may shed light on the nature of the neoplastic process itself.
肿瘤可对宿主产生多种远隔效应;这些效应被称为副肿瘤综合征。这些综合征可影响身体的任何系统,可在潜在肿瘤诊断之前或之后出现,其严重程度可能与肿瘤病程平行,也可能不平行。对这些综合征的诊断和治疗对医生来说可能具有挑战性,但成功的治疗可能会给患者带来显著的缓解。此外,这些综合征及其引发物质有时有助于某些肿瘤的诊断和病程监测。也许更重要的是,对肿瘤这些远隔效应的研究可能会揭示肿瘤形成过程本身的本质。