[固定化微生物进行的类固醇转化。I. 在有机溶剂中胆固醇向胆甾烯酮的转化]
[Steroid transformation with immobilized microorganisms. I. Transformation of cholesterol to cholestenone in organic solvents].
作者信息
Atrat P, Hüller E, Hörhold C
出版信息
Z Allg Mikrobiol. 1980;20(2):79-84. doi: 10.1002/jobm.3630200202.
PMID:6990643
Abstract
The transformation of cholesterol to cholest-4-ene-3-one has been investigated in the presence of toluene and carbontetrachloride using cells of Nocardia erythropolis (IMET 7185) immobilized by different methods. The adsorption on DEAE-cellulose has been observed to be the most effective method. The stability of immobilized cells relating to cholesteroloxydase activity, transformation capacity, and the influence of water have been investigated.
摘要
在甲苯和四氯化碳存在的条件下，使用通过不同方法固定化的红球诺卡氏菌（IMET 7185）细胞，研究了胆固醇向胆甾-4-烯-3-酮的转化。已观察到吸附在DEAE-纤维素上是最有效的方法。研究了固定化细胞与胆固醇氧化酶活性、转化能力以及水的影响相关的稳定性。
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