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囊性纤维化血清对普通变形杆菌的凝集反应

Proteus vulgaris agglutination by cystic fibrosis sera.

作者信息

Wang A, Turner M W, Soothill J F, Warner J O, Norman A P

出版信息

Arch Dis Child. 1980 Feb;55(2):130-3. doi: 10.1136/adc.55.2.130.

Abstract

The factor in sera of patients with cystic fibrosis (CF) and their parents which agglutinates Proteus vulgaris has characteristics similar to those of IgG antibody to this organism. Sera of patients without CF who have P. vulgaris infections agglutinate the organism similarly. At present there are too many false-positives in a control population for the test to be widely useful for heterozygote identification.

摘要

囊性纤维化(CF)患者及其父母血清中能凝集普通变形杆菌的因子具有与该生物体IgG抗体相似的特征。患有普通变形杆菌感染的非CF患者血清也能同样地凝集该生物体。目前,在对照人群中假阳性太多,以至于该检测无法广泛用于杂合子鉴定。

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本文引用的文献

3
Oyster ciliary inhibition by cystic fibrosis factor.囊性纤维化因子对牡蛎纤毛的抑制作用。
Science. 1969 Apr 18;164(3877):325-6. doi: 10.1126/science.164.3877.325.
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Cystic fibrosis heterozygosity in the pathogenesis of allergy.
Lancet. 1976 May 8;1(7967):990-1. doi: 10.1016/s0140-6736(76)91862-6.

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