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地西泮用于心肌梗死后即刻期。一项双盲试验。

Diazepam in immediate post-myocardial infarct period. A double blind trial.

作者信息

Dixon R A, Edwards I R, Pilcher J

出版信息

Br Heart J. 1980 May;43(5):535-40. doi: 10.1136/hrt.43.5.535.

DOI:10.1136/hrt.43.5.535
PMID:6990946
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC482337/
Abstract

One hundred and thirty-one male patients admitted to a coronary care unit with myocardial infarction, later confirmed, were randomly allocated to receive either 10 mg diazepam every six hours, or a matched placebo, for 48 hours. During this period, no differences were found between the treatment groups in the incidence of fatal or non-fatal tachyarrhythmias even when account was taken of differences in the severity of the initial infarct. Monitored blood pressure and heart rate data were comparable as were the patients' self-assessed anxiety levels and symptoms, except that drowsiness was more common in the patients treated with diazepam.

摘要

131名因心肌梗死入住冠心病监护病房的男性患者,后来确诊,被随机分配每6小时接受10毫克地西泮或匹配的安慰剂治疗,为期48小时。在此期间,即使考虑到初始梗死严重程度的差异,治疗组之间在致命或非致命性快速心律失常的发生率上也没有发现差异。监测的血压和心率数据相当,患者自我评估的焦虑水平和症状也相当,只是服用地西泮的患者嗜睡更为常见。

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本文引用的文献

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A CORONARY PROGNOSTIC INDEX FOR GRADING THE SEVERITY OF INFARCTION.一种用于评估梗死严重程度的冠状动脉预后指数。
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The adrenergic amines of human blood.人体血液中的肾上腺素能胺类物质。
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10
Treatment of acute myocardial infarction.急性心肌梗死的治疗
Ration Drug Ther. 1973 Sep;7(9):1-5.