[正常及白血病小鼠骨髓细胞对体外培养脾细胞抗体产生的抑制作用]
[Suppressive effect of bone marrow cells from normal and leukemic mice on antibody production in culture of spleen cells in vitro].
作者信息
Sidorovich I G, Pcheliniev S Iu, Khalmov R M
出版信息
Biull Eksp Biol Med. 1980;89(1):36-8.
PMID:6991020
Abstract
The suppressive effect of bone marrow cells from AKR and (CBA X C57BL)F1 mice aged 2--10 months on the immune response of syngeneic spleen cells to sheep red blood cells in vitro was investigated. It was shown that the suppressive action of leukemic mice bone marrow cells greatly increases by the age of 9--10 months as compared to 2-month age. In (CBA X C57BL)F1 mice the suppressive acitivty of bone marrow remains unchanged over the same time period.
摘要
研究了2至10月龄AKR小鼠及（CBA×C57BL）F1小鼠的骨髓细胞对同基因脾细胞体外抗绵羊红细胞免疫反应的抑制作用。结果表明，与2月龄相比，白血病小鼠骨髓细胞的抑制作用在9至10月龄时大大增强。在（CBA×C57BL）F1小鼠中，骨髓的抑制活性在同一时期保持不变。
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