[异种骨髓细胞对体外脾细胞培养中抗体形成的抑制作用]
[Suppressive effect of xenogenic bone marrow cells on antibody formation in a spleen cell culture in vitro].
作者信息
Vlasov A A, Sidorovich I G, Khaitov R M
出版信息
Biull Eksp Biol Med. 1980 Jul;89(7):77-9.
PMID:7407376
Abstract
Bone marrow cells from syngenetic and xenogeneic donors of different species were added to splenocyte culture to induce the primary immune response to sheep red blood cells. It has been shown that both xenogeneic and syngeneic bone marrow cells suppress the primary immune response in vitro. A conclusion is made that the suppressant effect exerted by bone marrow cells on the immune response of splenocytes is not liable to xenogenic restriction.
摘要
将来自不同物种的同基因和异基因供体的骨髓细胞添加到脾细胞培养物中，以诱导对绵羊红细胞的初次免疫反应。结果表明，异基因和同基因骨髓细胞均可在体外抑制初次免疫反应。由此得出结论，骨髓细胞对脾细胞免疫反应的抑制作用不受异种限制。
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