Iles J D
Can J Surg. 1980 May;23(3):288-90.
The value of ibuprofen (Motrin) as an analgesic was assessed in two consecutive studies in 425 patients with postherniorrhaphy pain. In the first study, 400 mg ibuprofen proved superior to placebo and as effective as one tablet of a compound containing 375 mg of acetylsalicylic acid, 30 mg caffeine and 8 mg codeine (ACC-8). In the second study, the analgesic effectiveness of 400 mg of ibuprofen was intermediate between that of two tablets of ACC-8 and one tablet of ACC-30 (a compound containing 375 mg ASA, 30 mg caffeine and 30 mg codeine). The side effects of all drugs were negligible. Ibuprofen should be a suitable alternative analgesic in postoperative pain of this type.
在两项针对425例疝修补术后疼痛患者的连续研究中，评估了布洛芬（Motrin）作为镇痛药的价值。在第一项研究中，400毫克布洛芬被证明优于安慰剂，且与一片含375毫克乙酰水杨酸、30毫克咖啡因和8毫克可待因的复方制剂（ACC - 8）效果相当。在第二项研究中，400毫克布洛芬的镇痛效果介于两片ACC - 8和一片ACC - 30（一种含375毫克乙酰水杨酸、30毫克咖啡因和30毫克可待因的复方制剂）之间。所有药物的副作用均可忽略不计。布洛芬应是这类术后疼痛合适的替代镇痛药。
