Campbell A, Chang R, Barker D, Ketner G
J Bacteriol. 1980 Jun;142(3):1025-8. doi: 10.1128/jb.142.3.1025-1028.1980.
Most mutants selected for derepression of the biotin operon required elevated concentrations of biotin for growth. Mutant extracts were deficient in holoenzyme synthetase activity.
大多数因生物素操纵子去阻遏而被选择的突变体需要提高生物素浓度才能生长。突变体提取物缺乏全酶合成酶活性。