眼部外炎症性疾病的免疫抑制治疗。

Immunosuppressive therapy for external ocular inflammatory disease.

作者信息

Foster C S

出版信息

Ophthalmology. 1980 Feb;87(2):140-50. doi: 10.1016/s0161-6420(80)35272-x.

PMID:6992019

Abstract

Fourteen patients with progressive ocular inflammation and destructive lesions, unresponsive to conventional therapy, were treated with systemic immunosuppression. Ten patients had connective tissue/vasculitis diseases; two, cicatricial pemphigoid; and two, bilateral Mooren's corneal ulcers. Control of underlying systemic disease by immunosuppression resulted invariably in concomitant control of ocular inflammation and destruction. Encouraging results were obtained in the patients with cicatricial pemphigoid and those with bilateral Mooren's ulcers.

摘要

14例患有进行性眼部炎症和破坏性病变且对传统治疗无反应的患者接受了全身免疫抑制治疗。其中10例患有结缔组织/血管炎疾病；2例患有瘢痕性类天疱疮；2例患有双侧蚕蚀性角膜溃疡。通过免疫抑制控制潜在的全身性疾病总是能同时控制眼部炎症和破坏。瘢痕性类天疱疮患者和双侧蚕蚀性角膜溃疡患者取得了令人鼓舞的结果。