血浆胆碱酯酶变体与麻醉医生。

Plasma cholinesterase variants and the anaesthetist.

作者信息

Whittaker M

出版信息

Anaesthesia. 1980 Feb;35(2):174-97. doi: 10.1111/j.1365-2044.1980.tb03800.x.

DOI:10.1111/j.1365-2044.1980.tb03800.x

Abstract

Biochemical properties of plasma cholinesterase of significance to the anaesthetist are reviewed. The role of the genetic variants of the enzyme in suxamethonium sensitivity and hyperthermia are discussed with emphasis on the pregnant patient. Altered gene frequencies of the enzyme variants in some mental disorders is commented upon.

摘要

本文综述了对麻醉医师具有重要意义的血浆胆碱酯酶的生化特性。讨论了该酶的基因变异在琥珀胆碱敏感性和高热中的作用，重点关注孕妇。还对某些精神障碍中酶变异的基因频率变化进行了评论。