肝移植术后生存率下降。
Decline in survival after liver transplantation.
作者信息
Starzl T E, Koep L, Porter K A, Schroter G P, Weil R, Hartley R B, Halgrimson C G
出版信息
Arch Surg. 1980 Jul;115(7):815-9. doi: 10.1001/archsurg.1980.01380070009002.
Abstract
Twenty-three recent cases of orthotopic liver transplantation were individually reviewed in an effort to determine why survival had declined from the 50% one-year survival rate of an immediately precedent series. In the series of 23, only six (26%) achieved one-year survival. Faulty case selection, technical complications, the use of damaged organs, and complications of immunosuppression were the main causes of death. Attention was directed to the possible use of preoperative lymphoid depletion to improve the effectiveness and safety of immunosuppression.
摘要
对最近23例原位肝移植病例进行了个案回顾，以确定为何生存率较前一组病例的一年生存率50%有所下降。在这23例病例中，只有6例（26%）存活了一年。病例选择不当、技术并发症、使用受损器官以及免疫抑制并发症是主要死亡原因。研究关注了术前淋巴细胞清除可能用于提高免疫抑制的有效性和安全性。
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本文引用的文献
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Surg Gynecol Obstet. 1979 Dec;149(6):815-21.
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Ann Surg. 1979 Oct;190(4):474-86. doi: 10.1097/00000658-197910000-00007.
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