Cantor K P, Fraumeni J F
Cancer Res. 1980 Aug;40(8 Pt 1):2645-52.
Age-adjusted mortality rates for non-Hodgkin's lymphoma in counties of the contiguous United States were examined by sex and race during 1950 to 1975 and were correlated through 1969 with demographic and industrial data. Mortality was consistently elevated in counties with large populations, especially in those with higher income and education levels. Among males, but not females, elevated rates appeared in counties with high percentages of residents of Russian or Greek descent. A series of contiguous counties with high rates was seen along the coast of California. Lower rates in the South were explained in a multivariate analysis by the generally lower socioeconomic levels in this region. Counties with industrial concentration in food packing showed higher mortality rates among males than did comparable counties without these industries. All regions and all sex-race groups showed an increase over time in mortality from non-Hodgkin's lymphoma, especially reticulum cell sarcoma.
1950年至1975年期间，按性别和种族对美国毗连各县非霍奇金淋巴瘤的年龄调整死亡率进行了研究，并在1969年之前将其与人口统计和工业数据进行了关联。人口众多的县死亡率持续升高，特别是在那些收入和教育水平较高的县。在男性中，而非女性中，俄罗斯或希腊裔居民比例较高的县死亡率升高。加利福尼亚海岸沿线出现了一系列死亡率较高的毗连县。在多变量分析中，南部地区较低的死亡率归因于该地区普遍较低的社会经济水平。食品包装行业集中的县男性死亡率高于没有这些行业的可比县。所有地区和所有性别-种族组非霍奇金淋巴瘤，尤其是网状细胞肉瘤的死亡率都随时间增加。
