Hiwada K, Kokubu T, Tokioka-Terao M
Clin Chim Acta. 1978 Sep 1;88(2):311-3. doi: 10.1016/0009-8981(78)90436-9.
A placental type of membrane-bound arylamidase was detected in serum and ascites from a patient with renal cell carcinoma by isoelectric focusing. The enzyme had the same molecular weight, electrophoretic mobility on polyacrylamide gel, isoelectric point and KM value as placental membrane-bound arylamidase. The new type of membrane-bound arylamidase was named Shiba-isoenzyme after the patient's name.
通过等电聚焦法在一名肾细胞癌患者的血清和腹水中检测到一种胎盘型膜结合芳基酰胺酶。该酶与胎盘膜结合芳基酰胺酶具有相同的分子量、在聚丙烯酰胺凝胶上的电泳迁移率、等电点和KM值。这种新型膜结合芳基酰胺酶以患者的名字命名为芝滨同工酶。