Hultberg B
Clin Chim Acta. 1978 Sep 15;88(3):441-8. doi: 10.1016/0009-8981(78)90279-6.
Isoelectric focusing was performed with six acid hydrolases in serum and liver tissue. Neuraminidase-treated serum and liver tissue were also examined. In general, acid hydrolases in sera seemed to be more sialylated than those in liver tissue. Serum from one patient with I-cell disease with increased activity of some acid hydrolases was found to have a normal isoelectric focusing pattern. These findings are discussed with respect to the uptake mechanism of acid hydrolases in serum.
采用等电聚焦法对血清和肝组织中的六种酸性水解酶进行了检测。同时也检测了经神经氨酸酶处理的血清和肝组织。总体而言，血清中的酸性水解酶似乎比肝组织中的酸性水解酶唾液酸化程度更高。发现一名患有I细胞病且某些酸性水解酶活性增加的患者的血清等电聚焦图谱正常。针对血清中酸性水解酶的摄取机制对这些发现进行了讨论。
