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分辨率为4.1埃的D-半乳糖结合蛋白的结构看起来像L-阿拉伯糖结合蛋白。

The structure of D-galactose-binding protein at 4.1 A resolution looks like L-arabinose-binding protein.

作者信息

Quiocho F A, Pflugrath J W

出版信息

J Biol Chem. 1980 Jul 25;255(14):6559-51.

PMID:6993475
Abstract

The structure of D-galactose-binding protein, a receptor for both high affinity active transport system and chemotaxis in Escherichia coli, has been solved at 4.1 A resolution using three heavy atom derivatives. The molecule is ellipsoidal with dimensions of about 65 X 35 X 35 A. The overall shape of the molecule and the indication that the molecule consists of two domains separated by a cleft are reminiscent of the structure of L-arabinose-binding protein.

摘要

D-半乳糖结合蛋白的结构已通过三种重原子衍生物以4.1埃的分辨率解析出来。该蛋白是大肠杆菌中高亲和力主动运输系统和趋化作用的受体。该分子呈椭圆形,尺寸约为65×35×35埃。分子的整体形状以及分子由被裂缝隔开的两个结构域组成的迹象让人联想到L-阿拉伯糖结合蛋白的结构。

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