Somani S M, Teece R G, Schaeffer D J
J Toxicol Environ Health. 1980 Mar;6(2):315-31. doi: 10.1080/15287398009529854.
Organic compounds were isolated from grab or composite samples of industrial and municipal discharges and of the Illinois River by liquid-liquid extraction or adsorption on activated carbon or XAD-2 resin columns. Of the 213 different compounds identified and semiquantitated by gas chromatography-mass spectrometry in 16 samples, 74 were long-chain hydrocarbons or their derivatives. Although their toxicological significance in the environment at the levels found is unknown, the widespread presence of these cocarcinogens and promoters (often found in conjunction with known initiators) may make them significant environmental toxicants. Some evidence for this is the fact that serial dilutions of the extracts were highly toxic to Salmonella typhimurium in the Ames assay, while weak mutagenicity was occasionally detected.
通过液-液萃取或吸附于活性炭或XAD-2树脂柱，从工业和城市排放物以及伊利诺伊河的抓取或混合样品中分离出有机化合物。在16个样品中通过气相色谱-质谱法鉴定并半定量的213种不同化合物中，74种是长链烃或其衍生物。尽管在所发现的水平下它们在环境中的毒理学意义尚不清楚，但这些辅助致癌物和促癌物（常与已知引发剂同时存在）的广泛存在可能使它们成为重要的环境毒物。对此的一些证据是，提取物的系列稀释液在艾姆斯试验中对鼠伤寒沙门氏菌具有高度毒性，同时偶尔检测到弱致突变性。
