Haines S J
Neurosurgery. 1980 Apr;6(4):355-61.
The clinical and experimental bases for antibiotic prophylaxis in surgery are reviewed briefly. The evidence regarding antibiotic prophylaxis in five specific neurosurgical situations (clean surgical procedures, cerebrospinal fluid shunts, external venticulostomies, basilar skull fractures, and compound skull fractures) is examined. There are no unequivocal indications for antibiotic prophylaxis in neurological surgery. Large scale randomized clinical trials will be required to settle the controversy in some of these areas.
简要回顾了外科手术中抗生素预防的临床和实验依据。研究了五种特定神经外科情况（清洁手术、脑脊液分流术、外部脑室造瘘术、颅底骨折和复合性颅骨骨折）中抗生素预防的证据。神经外科手术中尚无明确的抗生素预防指征。需要大规模随机临床试验来解决其中一些领域的争议。
