Haenszel W
Cancer. 1980 Aug 15;46(4 Suppl):957-60. doi: 10.1002/1097-0142(19800815)46:4+<957::aid-cncr2820461318>3.0.co;2-g.
Developments in the field of mammography as an adjunct screening procedure conducted at the Health Insurance Plan of Greater New York (HIP) are reviewed. As technology improves, new, non-invasive procedures for breast cancer screening may be proposed. Their test will pose the same problems encountered in the HIP trial: the definition of a control population receiving "conventional" screening; the rescreening of study and control women at specified intervals; the ability to maintain standardized diagnostic and treatment procedures for asymptomatic positives; long-term follow-up to determine whether a measurable reduction in breast cancer mortality in the study population has been achieved. These technical questions are capable of resolution and new or revised breast cancer screening modalities will be proposed, tested and possibly adopted in future years.
本文回顾了在纽约大健康保险计划（HIP）中作为辅助筛查程序的乳房X光检查领域的发展。随着技术的进步，可能会提出新的、非侵入性的乳腺癌筛查程序。它们的测试将带来与HIP试验中遇到的相同问题：接受“传统”筛查的对照人群的定义；在特定间隔对研究组和对照组女性进行重新筛查；对无症状阳性者维持标准化诊断和治疗程序的能力；长期随访以确定研究人群中乳腺癌死亡率是否有可测量的降低。这些技术问题是能够解决的，未来几年将提出、测试并可能采用新的或修订的乳腺癌筛查模式。
