长期摄入乙醇会增强宿主对金黄色葡萄球菌感染的易感性——通过葡聚糖免疫刺激进行调节。
Enhancement of host susceptibility to Staphylococcus aureus infection by chronic ethanol ingestion--modification by glucan immunostimulation.
作者信息
Di Luzio N R, Williams D L
出版信息
Alcohol Clin Exp Res. 1980 Jul;4(3):254-60. doi: 10.1111/j.1530-0277.1980.tb04810.x.
Abstract
The susceptibility of chronic ethanol-treated mice to S. aureus infection was ascertained, as was the ability of the immunostimulant glucan to modify ethanol-induced susceptibility to infection. Chronic alcohol-treated mice showed enhanced sensitivity to S. aureus. The administration of glucan significantly prolonged survival in S. aureus infected control and chronic ethanol mice.
摘要
确定了慢性乙醇处理小鼠对金黄色葡萄球菌感染的易感性，以及免疫刺激剂葡聚糖改变乙醇诱导的感染易感性的能力。慢性酒精处理的小鼠对金黄色葡萄球菌表现出更高的敏感性。给予葡聚糖显著延长了感染金黄色葡萄球菌的对照小鼠和慢性乙醇处理小鼠的存活时间。
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