Russell A S
Drugs. 1980 Aug;20(2):117-21. doi: 10.2165/00003495-198020020-00004.
Recrudescent herpes simplex infections and common warts are associated with evidence of immune depression. It was hoped that levamisole, a drug with immunomodulatory effects, would be helpful in both prophylaxis and therapy of these diseases. Despite enthusiasm from 'pilot' studies, properly carried out trials showed no benefit from levamisole as compared with a placebo. There is no good evidence for its efficacy in any other viral infection, but proper studies are still lacking.
复发性单纯疱疹感染和寻常疣与免疫抑制的证据相关。人们曾希望，具有免疫调节作用的药物左旋咪唑在这些疾病的预防和治疗中会有所帮助。尽管“试点”研究带来了热情，但与安慰剂相比，恰当实施的试验表明左旋咪唑并无益处。没有充分证据表明其在任何其他病毒感染中有效，但仍缺乏恰当的研究。
