DaMert G J, Kirkpatrick C H, Sohnle P G
Int Arch Allergy Appl Immunol. 1980;63(1):97-104. doi: 10.1159/000232614.
Antibody titers against Candida albicans and Pityrosporum orbiculare, the presumed etiologic agent of tinea versicolor, were determined in normal subjects, and in patients with tinea versicolor or chronic mucocutaneous candidiasis. Whereas antibody against both organisms was found in low titer in normal subjects, a majority of patients with each infection had elevated antibody titers against the infecting organism. Patients infected with one organism did not have elevated titers against the other, and titers against one did not correlate with titers against the other. Therefore, these studies indicate that both of the superficial infections are capable of inducing a significant humoral immune response and that actual infection with the organism rather than mere colonization is required for production of the elevated antibody titers.
在正常受试者以及花斑癣患者或慢性黏膜皮肤念珠菌病患者中，检测了针对白色念珠菌和圆形糠秕孢子菌（花斑癣的假定病原体）的抗体滴度。正常受试者中针对这两种微生物的抗体滴度较低，而每种感染的大多数患者针对感染微生物的抗体滴度升高。感染一种微生物的患者针对另一种微生物的抗体滴度并未升高，且针对一种微生物的滴度与针对另一种微生物的滴度不相关。因此，这些研究表明，这两种浅表感染均能够诱导显著的体液免疫反应，并且产生升高的抗体滴度需要实际感染该微生物而非仅仅是定植。
