Habal M B, Powell M L, Schimpff R D
J Biomed Mater Res. 1980 Jul;14(4):455-66. doi: 10.1002/jbm.820140412.
This short report concentrates on a close look at the immunological status of experimental animals which were implanted with a known dose of tumor and polymer implant. The implanted polymers used represented the most common biocompatible materials employed in current surgery. The immunological studies all were done in vitro on the cellular level. The studies suggested that there is a noticeable change of the immune system when inorganic biocompatible polymers are used in experimental animals.
本简短报告着重深入研究了植入已知剂量肿瘤和聚合物植入物的实验动物的免疫状态。所使用的植入聚合物代表了当前手术中最常用的生物相容性材料。所有免疫学研究均在细胞水平上进行体外实验。研究表明,当在实验动物中使用无机生物相容性聚合物时,免疫系统会发生显著变化。