Henschke F, Pesch H J
Microsc Acta Suppl. 1980;Suppl 4:124-8.
In 114 autopsy cases of both sexes, aged between 31 and 97 years and without bone disease, the influence of mechanical forces on the age-dependent remodelling of the spongy bone was determined in the 3rd and 5th lumbar vertebrae and the neck of the femur. For this purpose contrasty X-ray images of 100 mu thick polished bone sections were analysed using the LEITZ texture analysis system. The volumetric density and the surface density are highest in the neck of the femur, lowest in the 3rd lumbar vertebra, and almost as low in the 5th lumbar vertebra. The volumetric density decreases with increasing age by about one-third in all three bones. Correspondingly, the surface density also decreases in the lumbar vertebrae by one-third, but only by 18% in the neck of the femur. The specific surface reveals no age differences in the lumbar vertebrae, but increases by 19% in the neck of the femur. The constancy of the specific surface in the lumbar vertebrae can be explained by the fact that compensatory hypertrophy of the remaining trabeculae takes place. This compensatory growth of bone does not occur in the neck of the femur. The age-dependent decrease in spongy bone manifests itself in a residual spongiosa structure that depends on compressive forces in the case of the lumbar vertebrae and bending forces in the neck of the femur.
在114例年龄在31至97岁之间、无骨病的男女尸检病例中，研究了机械力对第三和第五腰椎以及股骨颈松质骨随年龄变化的重塑的影响。为此，使用LEITZ纹理分析系统对100微米厚的抛光骨切片的对比X射线图像进行了分析。体积密度和表面密度在股骨颈最高，在第三腰椎最低，在第五腰椎几乎同样低。在所有三块骨头中，体积密度均随着年龄增长而降低约三分之一。相应地，腰椎的表面密度也降低了三分之一，但股骨颈仅降低了18%。比表面积在腰椎中未显示出年龄差异，但在股骨颈中增加了19%。腰椎比表面积的恒定可以通过其余小梁发生代偿性肥大这一事实来解释。这种骨的代偿性生长在股骨颈中不会发生。松质骨随年龄的减少表现为一种残余松质结构，在腰椎中取决于压缩力，在股骨颈中取决于弯曲力。
