James A L, Barry R J
Schizophr Bull. 1980;6(3):506-25. doi: 10.1093/schbul/6.3.506.
Research on psychophysiological functioning in early onset psychosis is reviewed within the context of etiological formulations stressing perceptual and selective attention abnormalities. Electroencephalographic (EEG) measures, including resting EEG level, alpha blocking, average evoked response, and contingent negative variation, have received most attention in the literature; cardiovascular and electrodermal indices have not been so extensively explored in this group of children. While the nature of differential reactivity in early onset psychosis has not been thoroughly investigated, limited evidence suggests that the central behavioral anomalies associated with the condition may result from abnormal neurophysiological reactivity to sensory stimulation. Further studies of the psychophysiological functioning of these children should yield data useful in the clarification of etiology.
在强调感知和选择性注意异常的病因学框架下,对早发性精神病患者的心理生理功能研究进行了综述。脑电图(EEG)测量,包括静息EEG水平、α阻断、平均诱发电位和关联性负变,在文献中受到了最多关注;心血管和皮肤电指标在这组儿童中尚未得到如此广泛的研究。虽然早发性精神病患者差异反应性的本质尚未得到彻底研究,但有限的证据表明,与该疾病相关的中枢行为异常可能源于对感觉刺激的异常神经生理反应。对这些儿童心理生理功能的进一步研究应能产生有助于阐明病因的数据。