Furukawa F, Taniguchi S, Oguchi M, Komura J, Takiuchi H, Shirakawa S
Arch Dermatol. 1980 Aug;116(8):915-8.
An 86-year-old man had true histiocytic lymphoma of the skin. Diagnosis was established by the following findings: (1) typical histological features, (2) lack of receptors on tumor cells for immunological surface markers, and (3) active phagocytic function. Electron microscopic studies indicated cytoplasmic multivesicular bodies in the tumor cells. Multivesicular bodies have been reported in histiocytic proliferative disorders and may be of diagnostic value in cases of true histiocytic lymphoma.
一名86岁男性患有皮肤真性组织细胞淋巴瘤。诊断依据以下发现确立：（1）典型的组织学特征，（2）肿瘤细胞缺乏免疫表面标志物的受体，以及（3）活跃的吞噬功能。电子显微镜研究显示肿瘤细胞中有细胞质多囊泡体。多囊泡体已在组织细胞增生性疾病中被报道，可能对真性组织细胞淋巴瘤病例具有诊断价值。
