Patel C V, Koppikar M G, Patel M S, Parulkar G B
Curr Med Res Opin. 1980;6(9):624-9. doi: 10.1185/03007998009109499.
A double-blind trial was carried out in 100 patients with moderate to severe post-operative pain to compare the analgesic effectiveness over a 6-hour period of single intramuscular injections of 2.5 g dipyrone and 100 mg pethidine. Maximum pain relief was seen 2 hours after drug administration in both groups and there was no statistically significant difference in responses. No side-effects were reported.
对100例中重度术后疼痛患者进行了一项双盲试验,以比较单次肌内注射2.5g安乃近和100mg哌替啶在6小时内的镇痛效果。两组在给药后2小时均出现最大程度的疼痛缓解,且反应无统计学显著差异。未报告有副作用。