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胃肠外用药安乃近与哌替啶治疗术后疼痛的双盲比较

A double-blind comparison of parenteral dipyrone and pethidine in the treatment of post-operative pain.

作者信息

Patel C V, Koppikar M G, Patel M S, Parulkar G B

出版信息

Curr Med Res Opin. 1980;6(9):624-9. doi: 10.1185/03007998009109499.

Abstract

A double-blind trial was carried out in 100 patients with moderate to severe post-operative pain to compare the analgesic effectiveness over a 6-hour period of single intramuscular injections of 2.5 g dipyrone and 100 mg pethidine. Maximum pain relief was seen 2 hours after drug administration in both groups and there was no statistically significant difference in responses. No side-effects were reported.

摘要

对100例中重度术后疼痛患者进行了一项双盲试验,以比较单次肌内注射2.5g安乃近和100mg哌替啶在6小时内的镇痛效果。两组在给药后2小时均出现最大程度的疼痛缓解,且反应无统计学显著差异。未报告有副作用。

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