Daftary S N, Mehta A C, Nanavati M
Curr Med Res Opin. 1980;6(9):614-8. doi: 10.1185/03007998009109497.
A double-blind, placebo-controlled trial was carried out in 299 patients suffering from post-episiotomy pain to compare the analgesic effectiveness and tolerance of single doses of 500 mg dipyrone and 500 mg paracetamol. Assessments of pain relief over a 6-hour period showed that dipyrone produced significantly better results than placebo within half an hour of intake and maintained this superiority throughout the 6 hours. It also afforded consistently better pain relief than paracetamol and was significantly more effective at the 6-hour assessment. Side-effects were few and mild.
对299例患有会阴切开术后疼痛的患者进行了一项双盲、安慰剂对照试验,以比较单次服用500毫克安乃近和500毫克对乙酰氨基酚的镇痛效果和耐受性。6小时内的疼痛缓解评估显示,安乃近在摄入后半小时内产生的效果明显优于安慰剂,并在整个6小时内保持这种优势。它还始终比扑热息痛能更好地缓解疼痛,在6小时评估时效果显著更佳。副作用少且轻微。