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双氯芬酸与对乙酰氨基酚用于会阴切开术后疼痛的对照比较。

A controlled comparison of dipyrone and paracetamol in post-episiotomy pain.

作者信息

Daftary S N, Mehta A C, Nanavati M

出版信息

Curr Med Res Opin. 1980;6(9):614-8. doi: 10.1185/03007998009109497.

DOI:10.1185/03007998009109497
PMID:6996931
Abstract

A double-blind, placebo-controlled trial was carried out in 299 patients suffering from post-episiotomy pain to compare the analgesic effectiveness and tolerance of single doses of 500 mg dipyrone and 500 mg paracetamol. Assessments of pain relief over a 6-hour period showed that dipyrone produced significantly better results than placebo within half an hour of intake and maintained this superiority throughout the 6 hours. It also afforded consistently better pain relief than paracetamol and was significantly more effective at the 6-hour assessment. Side-effects were few and mild.

摘要

对299例患有会阴切开术后疼痛的患者进行了一项双盲、安慰剂对照试验,以比较单次服用500毫克安乃近和500毫克对乙酰氨基酚的镇痛效果和耐受性。6小时内的疼痛缓解评估显示,安乃近在摄入后半小时内产生的效果明显优于安慰剂,并在整个6小时内保持这种优势。它还始终比扑热息痛能更好地缓解疼痛,在6小时评估时效果显著更佳。副作用少且轻微。

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1
A controlled comparison of dipyrone and paracetamol in post-episiotomy pain.双氯芬酸与对乙酰氨基酚用于会阴切开术后疼痛的对照比较。
Curr Med Res Opin. 1980;6(9):614-8. doi: 10.1185/03007998009109497.
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A comparison of four analgesics in post-episiotomy pain.四种镇痛药用于会阴切开术后疼痛的比较。
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引用本文的文献

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Paracetamol/acetaminophen (single administration) for perineal pain in the early postpartum period.对产后早期会阴部疼痛,单次给予扑热息痛/对乙酰氨基酚(acetaminophen)。
Cochrane Database Syst Rev. 2021 Jan 8;1(1):CD008407. doi: 10.1002/14651858.CD008407.pub3.
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Oral non-steroidal anti-inflammatory drugs (single dose) for perineal pain in the early postpartum period.口服非甾体抗炎药(单次剂量)用于产后早期会阴疼痛。
Cochrane Database Syst Rev. 2021 Jan 11;1(1):CD011352. doi: 10.1002/14651858.CD011352.pub3.
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Oral non-steroidal anti-inflammatory drugs (single dose) for perineal pain in the early postpartum period.
口服非甾体抗炎药(单剂量)用于产后早期会阴部疼痛
Cochrane Database Syst Rev. 2016 Jul 14;7(7):CD011352. doi: 10.1002/14651858.CD011352.pub2.
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Single dose dipyrone (metamizole) for acute postoperative pain in adults.单剂量安乃近用于成人术后急性疼痛
Cochrane Database Syst Rev. 2016 Apr 20;4(4):CD011421. doi: 10.1002/14651858.CD011421.pub2.
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WITHDRAWN: Single dose dipyrone for acute postoperative pain.撤回:单剂量安乃近用于术后急性疼痛。
Cochrane Database Syst Rev. 2013 Nov 25;2013(11):CD003227. doi: 10.1002/14651858.CD003227.pub3.
6
Single dose dipyrone for acute postoperative pain.单剂量安乃近用于术后急性疼痛。
Cochrane Database Syst Rev. 2010 Sep 8(9):CD003227. doi: 10.1002/14651858.CD003227.pub2.
7
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Cochrane Database Syst Rev. 2008 Oct 8;2008(4):CD004602. doi: 10.1002/14651858.CD004602.pub2.
8
[The role of non-opioid analgesics in the management of postoperative pain.].
Schmerz. 1993 Jun;7(2):97-106. doi: 10.1007/BF02527866.
9
[Not Available].[不可用]。
Schmerz. 1988 Sep;2(3):170-2. doi: 10.1007/BF02528620.
10
The opiate-sparing effect of dipyrone in post-operative pain therapy with morphine using a patient-controlled analgesic system.使用患者自控镇痛系统时,安乃近在吗啡术后疼痛治疗中的阿片类药物节省效应。
Intensive Care Med. 1996 Oct;22(10):1043-7. doi: 10.1007/BF01699225.