静脉注射乙酰水杨酸与安乃近用于术后疼痛的比较：中期报告
Comparison of intravenous acetylsalicylic acid and dipyrone in postoperative pain: an interim report.
作者信息
Blendinger I, Eberlein H J
出版信息
Br J Clin Pharmacol. 1980 Oct;10 Suppl 2(Suppl 2):339S-341S. doi: 10.1111/j.1365-2125.1980.tb01819.x.
Abstract
1 In 17 gynaecological patients with postoperative pain the analgesic efficacy of intravenous lysine salicylate 1.8 g (corresponding to acetylsalicylic acid (ASA) 1.0 g) and dipyrone 1.0 g were compared in a double-blind randomized study. 2 In the ASA group, mean pain relief and pain intensity difference scores reached a maximum 30 min after drug administration and remained at this level for the next 90 minutes. 3 In the dipyrone group, these scores reached their peak 60 min after drug administration and seemed to fall off during the next hour. 4 The mean pain relief and intensity difference scores were greater following aspirin than dipyrone. However, firm conclusions cannot be drawn from the results of this small study.
摘要
- 在一项双盲随机研究中，比较了静脉注射1.8克赖氨酸水杨酸盐（相当于1.0克乙酰水杨酸（ASA））和1.0克安乃近对17名有术后疼痛的妇科患者的镇痛效果。2. 在ASA组中，平均疼痛缓解和疼痛强度差异评分在给药后30分钟达到最大值，并在接下来的90分钟内保持在该水平。3. 在安乃近组中，这些评分在给药后60分钟达到峰值，并在接下来的一小时内似乎有所下降。4. 阿司匹林后的平均疼痛缓解和强度差异评分高于安乃近。然而，从这项小型研究的结果中无法得出确凿的结论。
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