Djawari D, Lukaschek E, Jecht E
Dermatologica. 1980;161(4):233-7. doi: 10.1159/000250370.
A cellular immunodeficiency was revealed in a 39-year-old female patient suffering from Werner's syndrome. Relevant findings were negative intracutaneous tests to candidin, trichophytin, tuberculin and bacterial antigens, reduced lymphocyte response to PHA, and impaired intracellular killing of Candida albicans by granulocytes. The inclination of patients suffering from Werner's syndrome to develop neoplasms may be related to this immunodeficiency.
在一名患有沃纳综合征的39岁女性患者中发现了细胞免疫缺陷。相关检查结果包括对念珠菌素、毛癣菌素、结核菌素和细菌抗原的皮内试验呈阴性，淋巴细胞对PHA的反应降低，以及粒细胞对白色念珠菌的细胞内杀伤受损。沃纳综合征患者发生肿瘤的倾向可能与此免疫缺陷有关。
