Newman R A, Boss M A
Immunology. 1980 Jun;40(2):193-200.
Haemopoietic cells from several murine organs were examined for the presence of peanut agglutinin (PNA) receptors. Foetal liver and adult bone marrow contained a number of cells, which were PNA+ but did not stain with conventional T and B markers. Some of the PNA+ cells, however, were pre-B cells, as shown by the presence of cytoplasmic IgM in the absence of cell surface Ig. Cells in the T lineage retained their PNA receptors during maturation, although these became masked by sialic acid on mature peripheral blood T cells. Cells of the B lineage, in contrast, gradually lost their PNA receptors as they matured from pre-B to mature surface immunoglobulin positive B lymphocytes.
对来自几只小鼠器官的造血细胞进行了检测，以确定是否存在花生凝集素（PNA）受体。胎肝和成年骨髓含有许多细胞，这些细胞PNA呈阳性，但用传统的T和B标记物染色时不着色。然而，一些PNA阳性细胞是前B细胞，这通过在没有细胞表面免疫球蛋白的情况下存在细胞质IgM得以证明。T系细胞在成熟过程中保留了它们的PNA受体，尽管这些受体在成熟的外周血T细胞上被唾液酸掩盖。相比之下，B系细胞从前B细胞成熟为成熟的表面免疫球蛋白阳性B淋巴细胞时，逐渐失去了它们的PNA受体。
