人表皮细胞在体外合成的大疱性类天疱疮抗原。
Bullous pemphigoid antigen synthesized in vitro by human epidermal cells.
作者信息
Woodley D, Didierjean L, Regnier M, Saurat J, Prunieras M
出版信息
J Invest Dermatol. 1980 Aug;75(2):148-51. doi: 10.1111/1523-1747.ep12522536.
PMID:6997396
Abstract
Cultured living human epidermal cells migrating on the surface of irradiated non-viable pig dermis, were found to produce bullous pemphigoid antigen at the epidermis-pig dermal junction between days 10 and 50 in culture. In certain series, the antigen was detected within the cytoplasm of the basal cells as well. These findings suggest that the bullous pemphigoid antigen is synthesized by epidermal cells.
摘要
在培养的第10天至50天期间，发现培养的活的人表皮细胞在辐照后的无活力猪真皮表面迁移时，在表皮 - 猪真皮交界处产生大疱性类天疱疮抗原。在某些实验系列中，在基底细胞的细胞质内也检测到了该抗原。这些发现表明大疱性类天疱疮抗原是由表皮细胞合成的。
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