Sehgal S, Datta B N, Chugh K S, Aikat B K, Datta D V
Clin Exp Immunol. 1980 Jun;40(3):453-8.
Twenty-two patients dying of acute viral hepatitis were studied for the presence of renal immune complexes using direct immunofluorescence. A detailed light microscopic study of liver, kidney and other organs was also done and sera scanned for the presence of HBsAg. Results of light microscopy indicate that thirteen of twenty-two patients showed mild to moderate glomerular abnormalities. Immunofluorescence was positive in fifteen of twenty-two patients. IgA being positive in 28%. The incidence of HBsAg was low. It is suggested that both B and non-B type of hepatitis viruses are associated with a high incidence of renal immune complexes along with morphological alterations in the glomerulus.
对22例死于急性病毒性肝炎的患者进行了研究，采用直接免疫荧光法检测肾脏免疫复合物的存在情况。同时对肝脏、肾脏和其他器官进行了详细的光镜检查，并检测血清中HBsAg的存在情况。光镜检查结果显示，22例患者中有13例表现出轻度至中度肾小球异常。22例患者中有15例免疫荧光呈阳性。IgA阳性率为28%。HBsAg的发生率较低。提示B型和非B型肝炎病毒均与肾脏免疫复合物的高发生率以及肾小球形态学改变有关。
