Gemant A
Mol Biol Rep. 1977 Jun;3(4):283-7. doi: 10.1007/BF00368298.
The oxidation of essential serum proteins, albumin and gamma globulin, by the enzyme peroxidase can be partially inhibited by compounds, such as EDTA and 2,4-pentanedione, that complex with the iron ion in peroxidase. The importance of such inhibition lies in the circumstance that the oxidations in question might be a possible causative factor in tissue aging.
过氧化物酶对血清中的必需蛋白质(白蛋白和γ球蛋白)的氧化作用,可被诸如乙二胺四乙酸(EDTA)和2,4-戊二酮等能与过氧化物酶中的铁离子络合的化合物部分抑制。这种抑制作用的重要性在于,上述氧化作用可能是组织衰老的一个潜在致病因素。