Walker G S, Peacock M, Marshall D H, Giles G R, Davison A M
Nephron. 1980;26(5):225-9. doi: 10.1159/000181989.
After successful renal transplantation there is continuing malabsorption of calcium and phosphorus. This is due in part to impaired glomerular filtration rate, and in part to the action of steroid on calcium and phosphorus absorption. The effect of steroids is most marked over the first 18 months after transplantation and causes significant malabsorption of calcium and phosphorus even though good graft function is established. Calcium and phosphorus malabsorption can be improved by exogenous 1,25-dihydroxy vitamin D (oral 1 alpha-OH D3 or 1,25-[OH]2D3).
肾移植成功后，钙和磷持续吸收不良。这部分是由于肾小球滤过率受损，部分是由于类固醇对钙和磷吸收的作用。类固醇的影响在移植后的前18个月最为明显，即使移植肾功能良好，也会导致钙和磷的显著吸收不良。外源性1,25 - 二羟基维生素D（口服1α - 羟化维生素D3或1,25 - [OH]2D3）可改善钙和磷的吸收不良。
