骨佩吉特病中的骨组织。超微结构与免疫细胞学。
Bone tissue in Paget's disease of bone. Ultrastructure and Immunocytology.
作者信息
Rebel A, Basle M, Pouplard A, Malkani K, Filmon R, Lepatezour A
出版信息
Arthritis Rheum. 1980 Oct;23(10):1104-14. doi: 10.1002/art.1780231006.
Ultrastructural observation in Paget's disease of bone clarify aspects of bone cells in bone tissue and demonstrate the presence of specific intranuclear inclusions composed of microcylinders in the osteoclasts. The morphologic analysis of these structures suggests an analogy with virus material of the measles group. Results obtained using indirect immunofluorescence and immunoperoxidase techniques lend further support to the hypothesis of a viral etiology in Paget's disease of bone.
骨Paget病的超微结构观察阐明了骨组织中骨细胞的一些方面，并证实在破骨细胞中存在由微圆柱体组成的特定核内包涵体。对这些结构的形态学分析表明与麻疹病毒组的病毒物质类似。使用间接免疫荧光和免疫过氧化物酶技术获得的结果进一步支持了骨Paget病病毒病因学的假说。
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