Rozenshtraukh L V, Chikharev V N
Biull Eksp Biol Med. 1980 Sep;90(9):303-5.
The effects of ethmozine (2 X 10(-5) g/ml) and diethylamine derivative of ethmozine (DAD of ethmozine) (2 X 10(-5) g/ml) on slow inward and outward currents were investigated by means of the voltage clamp method in frog auricular trabeculae. Ethmozine increased the maximal value of the slow inward current by 62 +/- 11% (n = 5) while DAD of ethmozine decreased it by 54 +/- 17% (n = 3). The control value of the slow inward current was restored after 30 min of wash out. Ethmozine and DAD of ethmozine had no significant effect on steady-state outward current.
采用电压钳法在蛙心耳小梁上研究了乙吗噻嗪（2×10⁻⁵ g/ml）及其二乙胺衍生物（乙吗噻嗪二乙胺衍生物，2×10⁻⁵ g/ml）对慢内向和外向电流的影响。乙吗噻嗪使慢内向电流的最大值增加了62±11%（n = 5），而乙吗噻嗪二乙胺衍生物使其降低了54±17%（n = 3）。洗脱30分钟后，慢内向电流的对照值恢复。乙吗噻嗪及其二乙胺衍生物对稳态外向电流无显著影响。
