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叙利亚金黄地鼠呼吸道中碘和氯化铁对苯并(a)芘的致癌激活作用。

Carcinogenic activation of benzo(a)pyrene by iodine and ferric chloride in the respiratory tract of Syrian golden hamsters.

作者信息

Stenbäck F, Rowland J

出版信息

Experientia. 1978 Aug 15;34(8):1065-6. doi: 10.1007/BF01915351.

DOI:10.1007/BF01915351
PMID:700030
Abstract

Benzo(a)pyrene (0.5 mg), in itself weakly carcinogenic, when given in combination with ferric chloride (0.16 mg) or iodine (0.2 mg), alone noncarcinogen, induced a number of tumors of different parts of the respiratory tract of Syrian golden hamsters.

摘要

苯并(a)芘（0.5毫克）本身致癌性较弱，与氯化铁（0.16毫克）或碘（0.2毫克，本身无致癌性）联合使用时，诱发了叙利亚金仓鼠呼吸道不同部位的多种肿瘤。

相似文献

1
Carcinogenic activation of benzo(a)pyrene by iodine and ferric chloride in the respiratory tract of Syrian golden hamsters.叙利亚金黄地鼠呼吸道中碘和氯化铁对苯并(a)芘的致癌激活作用。
Experientia. 1978 Aug 15;34(8):1065-6. doi: 10.1007/BF01915351.
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Clearance of benzo(a)pyrene from the respiratory tract of hamsters following its intratracheal instillation with or without ferric oxide.
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Production of respiratory tract tumors in hamsters by benzo(a)pyrene.
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Investigations on the carcinogenic burden by air pollution in man. Intratracheal instillation studies with benzo[a]pyrene in a mixture of Tris buffer and saline in Syrian golden hamsters.
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The effect of respiratory carcinogenesis on systemic humoral and cell-mediated immunity of Syrian golden hamsters.
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Investigations on the carcinogenic burden by air pollution in man. Intratracheal instillation studies with benzo(a)pyrene in bovine serum albumin in Syrian hamsters.关于空气污染对人体致癌负荷的调查。叙利亚仓鼠气管内滴注苯并(a)芘与牛血清白蛋白的研究。
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Modifying effect of dietary fat on benzo[a]pyrene-induced respiratory tract tumours in hamsters.
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Modifying effect of vitamin A on benzo[a]pyrene-induced respiratory tract tumours in hamsters.
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A critical appraisal of intratracheal instillation of benzo[a]pyrene to Syrian golden hamsters as a model in respiratory tract carcinogenesis.
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Respiratory tract tumours in hamsters exposed to acetaldehyde vapour alone or simultaneously to benzo(a)pyrene or diethylnitrosamine.单独暴露于乙醛蒸汽或同时暴露于苯并(a)芘或二乙基亚硝胺的仓鼠呼吸道肿瘤。
Eur J Cancer Clin Oncol. 1982 Jan;18(1):13-31. doi: 10.1016/0277-5379(82)90020-7.

引用本文的文献

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Evaluation of mixed exposure to carcinogens and correlations of in vivo and in vitro systems.致癌物混合暴露评估及体内外系统的相关性
Environ Health Perspect. 1983 Jan;47:319-24. doi: 10.1289/ehp.8347319.

本文引用的文献

1
EXPERIMENTAL STUDIES OF THE CONDITIONS OF EXPOSURE TO CARCINOGENS FOR LUNG CANCER INDUCTION.肺癌诱发中致癌物暴露条件的实验研究。
J Air Pollut Control Assoc. 1965 Jan;15:23-5. doi: 10.1080/00022470.1965.10468328.
2
EVIDENCE FOR THE BINDING OF POLYNUCLEAR AROMATIC HYDROCARBONS TO THE NUCLEIC ACIDS OF MOUSE SKIN: RELATION BETWEEN CARCINOGENIC POWER OF HYDROCARBONS AND THEIR BINDING TO DEOXYRIBONUCLEIC ACID.多环芳烃与小鼠皮肤核酸结合的证据：烃类致癌能力与其与脱氧核糖核酸结合之间的关系。
Nature. 1964 May 23;202:781-4. doi: 10.1038/202781a0.
3
Copper acetate as an accelerator in mouse skin carcinogenesis by 9,10-dimethyl-1,2-benzanthracene.
乙酸铜作为9,10-二甲基-1,2-苯并蒽诱发小鼠皮肤癌的促进剂。
Experientia. 1965 Jul 15;21(7):415-6. doi: 10.1007/BF02139778.
4
A microsome-dependent binding of benzo[a]pyrene to DNA.微粒体介导的苯并[a]芘与DNA的结合。
Cancer Res. 1969 Jun;29(6):1272-6.
5
A method for the experimental induction of bronchogenic carcinoma.一种实验性诱导支气管源性癌的方法。
Cancer Res. 1968 Jan;28(1):104-24.
6
Molecular characteristics of some carcinogenic hydrocarbons.某些致癌烃的分子特征。
Proc Natl Acad Sci U S A. 1971 Jun;68(6):1251-3. doi: 10.1073/pnas.68.6.1251.
7
Isolation and degradation of DNA from cells treated with tritium-labeled 7,12-dimethylbenz(a)anthracene: studies on the nature of the binding of this carcinogen to DNA.
Cancer Res. 1969 Jan;29(1):157-65.
8
Rat liver phenylalanine hydroxylase, an iron enzyme.大鼠肝脏苯丙氨酸羟化酶，一种含铁酶。
J Biol Chem. 1972 Aug 25;247(16):5161-7.
9
Enzyme-catalysed reactions of polycyclic hydrocarbons with deoxyribonucleic acid and protein in vitro.多环烃在体外与脱氧核糖核酸及蛋白质的酶催化反应。
Biochem J. 1968 Nov;110(1):159-60. doi: 10.1042/bj1100159.