Matek W, Frühmorgen P, Kaduk B, Reidenbach H D, Bodem F, Demling L
Endoscopy. 1980 Sep;12(5):231-6. doi: 10.1055/s-2007-1021750.
Fifty experimentally induced, standardized gastric bleeding lesions were successfully arrested in the dog using electrocoagulation with simultaneous instillation of water (EHT-coagulation). The contact pressure of the coagulating electrode was kept almost constant by means of a spring mechanism. The coagulated lesions healed without secondary enlargement of the coagulation effect and without complication. No secondary perforations were observed. Even when coagulation was carried out at an output power about 30% higher than the mimimum power necessary for reliable hemostatic coagulation, no complications were observed. Only with additional post bleeding arrest coagulation in excess of 10 seconds at this higher output, were two primary performations produced in 2 out of 12 cases. The non-perforated remaining 10 lesions healed without complication. With additional coagulation (at power output setting 6 for 20 seconds - 8 cases; at power setting 7 for 10 seconds - 6 cases), no perforations were observed and healing was without complications. Thus, in animal experiments, the therapeutic range for the arrest of bleeding using the electro-hydro-thermo-electrode is adequately large. The technique should be tested in clinical trials.
采用电凝并同时注入水（EHT 凝血法），成功止住了 50 个实验诱导的、标准化的犬胃出血性损伤。通过弹簧装置使凝血电极的接触压力几乎保持恒定。凝血损伤愈合，凝血效果无继发性扩大，且无并发症。未观察到继发性穿孔。即使在高于可靠止血凝血所需最小功率约 30%的输出功率下进行凝血，也未观察到并发症。仅在以这种较高输出功率额外进行超过 10 秒的出血后止血凝血时，12 例中有 2 例出现了原发性穿孔。其余 10 个未穿孔的损伤愈合且无并发症。进行额外凝血（功率输出设置为 6 持续 20 秒 - 8 例；功率设置为 7 持续 10 秒 - 6 例）时，未观察到穿孔，愈合也无并发症。因此，在动物实验中，使用电热电极止血的治疗范围足够大。该技术应在临床试验中进行测试。
