Swain C P, Mills T N, Shemesh E, Dark J M, Lewin M R, Clifton J S, Northfield T C, Cotton P B, Salmon P R
Gut. 1984 Dec;25(12):1424-31. doi: 10.1136/gut.25.12.1424.
Several inexpensive endoscopic methods of electrocoagulation have been advocated for treatment of gastrointestinal haemorrhage. We compared four types of electrode: dry monopolar - Cameron Miller (M), liquid monopolar - Storz (L), bipolar - Bicap ACMI (B), and heater probe - Seattle (H). The electrical and thermal properties of these probes were studied using computerised monitoring of energy deposition and their efficacy and safety was tested in a randomised study in 140 experimental canine gastric ulcers. At optimal pulse settings 20J (M), 70J (L), 17J (B), 15J (H), effective haemostasis was achieved in all ulcers, the mean number of pulses being M5, L6, H6 and B11, the first three requiring significantly (p less than 0.01) less pulse than B. Relative safety of the electrodes was assessed by comparing the incidence of full thickness damage at histology: B24%, H20%, L58% and M69%; B and H proving significantly (p less than 0.01) safer than L and M. Sticking was assessed as H greater than B greater than M much greater than L. Insensitivity to extreme angulation and force of application was assessed as L greater than B greater than M (H is preset). Of the two safer electrodes the heater probe was more effective than the bipolar probe. Despite its greater tendency to stick than the other devices, the heater probe appeared the most promising of the endoscopic electrodes tested.
已有几种廉价的内镜电凝方法被推荐用于治疗胃肠道出血。我们比较了四种电极:干式单极——卡梅伦·米勒(M)、液式单极——斯托兹(L)、双极——比卡普ACMI(B)和热探头——西雅图(H)。使用计算机监测能量沉积研究了这些探头的电学和热学特性,并在140只实验性犬胃溃疡的随机研究中测试了它们的有效性和安全性。在最佳脉冲设置下,20焦耳(M)、70焦耳(L)、17焦耳(B)、15焦耳(H),所有溃疡均实现有效止血,平均脉冲数分别为M5、L6、H6和B11,前三种所需脉冲数明显(p小于0.01)少于B。通过比较组织学上全层损伤的发生率评估电极的相对安全性:B为24%,H为20%,L为58%,M为69%;结果表明B和H比L和M明显(p小于0.01)更安全。粘连情况评估为H大于B大于M远大于L。对极端角度和施加力的不敏感性评估为L大于B大于M(H为预设值)。在两种更安全的电极中,热探头比双极探头更有效。尽管热探头比其他设备更容易粘连,但它似乎是所测试的内镜电极中最有前景的。