Loewenstein W R, Kanno Y, Socolar S J
Fed Proc. 1978 Oct;37(12):2645-50.
Cells of most organized tissues are interconnected at their junctions by aqueous membrane channels, shown in one instance to be at least 14--16 A in diameter. During junction formation, nascent channels are detected as quantal steps in cell-to-cell conductance, growing progressively in number. The channels detected are stable. Elevation of cytoplasmic free Ca2+ concentration can cause graded closure of channels.
大多数有组织的组织中的细胞在其连接处通过水膜通道相互连接,在一个实例中显示其直径至少为14 - 16埃。在连接形成过程中,新生通道被检测为细胞间电导的量子步骤,数量逐渐增加。检测到的通道是稳定的。细胞质游离Ca2+浓度的升高可导致通道分级关闭。