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[立体定向丘脑切开术治疗幻肢痛综合征]

[Stereotaxic thalamotomy in the phantom pain syndrome].

作者信息

Vasin N Ia, Grokhovskiĭ N P

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 1980 Sep-Oct(5):16-23.

PMID:7001820
Abstract

The results of stereotaxic thalamotomy in 18 patients suffering from a severe phantom-pain syndrome are described. It is shown that to achieve a more stable analgetic effect and a reduced emotional background of pain perception it is expedient, parallel with the destruction of the somatotopic zones of the relay posterior ventral nucleus, which have a bearing on pains in the phantom, to also exclude the non-specific afferent systems of the thalamus, that is, the median center, bordering nucleus and oroventral part of the cushion of the optic thalamus. The effects of the electrostimulation of these structures of the thalamus are described in the process of their intraoperational physiological identification. It is shown that the combined destruction of specific and non-specific afferent structures of the optic thalamus in most cases ensures a considerable diminution or disappearance of phantom pain permitting patients to readapt themselves to normal everyday life.

摘要

本文描述了对18例患有严重幻肢痛综合征患者进行立体定向丘脑切开术的结果。结果表明,为了获得更稳定的镇痛效果并减轻疼痛感知的情绪背景,除了破坏与幻肢痛相关的后腹侧核的躯体定位区外,还应排除丘脑的非特异性传入系统,即丘脑正中核、边界核以及丘脑枕的口腹侧部分。文中还描述了在手术过程中对这些丘脑结构进行电刺激时的生理识别过程。结果表明,在大多数情况下,联合破坏丘脑的特异性和非特异性传入结构可使幻肢痛显著减轻或消失,从而使患者能够重新适应正常的日常生活。

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