5岁以下儿童的肾移植
Renal transplantation in children less than 5 years of age.
作者信息
Rizzoni G, Malekzadeh M H, Pennisi A J, Ettenger R B, Uittenbogaart C H, Fine R N
出版信息
Arch Dis Child. 1980 Jul;55(7):532-6. doi: 10.1136/adc.55.7.532.
19 young children (less than 5 years old) have received 31 renal transplants from 4 live relatives and 27 cadaver donors. The 2-year allograft survival rate for the patients receiving their 1st allograft from the 4 live donors was 75 +/- 22% while for the patients receiving their 1st allograft from 15 cadaver donors was 26 +/- 11%. 10 children are currently surviving with functioning allographs (7 cadavers and 3 live relatives); 4 have died and 5 are undergoing dialysis after the loss of at least one allograft. Despite the poor allograft survival rate the fact that 7 children are surviving with cadaver allografts indicates that the lack of a living related donor should not prevent transplants in young children.
19名幼儿（年龄小于5岁）接受了来自4名活体亲属供者和27名尸体供者的31次肾移植。从4名活体供者接受首次移植的患者，其移植肾2年存活率为75±22%，而从15名尸体供者接受首次移植的患者，其移植肾2年存活率为26±11%。目前，10名患儿依靠功能良好的移植肾存活（7名尸体供肾和3名活体亲属供肾）；4名患儿已死亡，5名患儿在至少一个移植肾失功后正在接受透析治疗。尽管移植肾存活率较低，但7名患儿依靠尸体供肾存活这一事实表明，缺乏活体亲属供者不应妨碍对幼儿进行移植手术。
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