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罗非奈德对雏鸭鸭疫里默氏杆菌和大肠杆菌感染的控制作用

Rofenaid in the control of Pasteurella anatipestifer and Escherichia coli infections in ducklings.

作者信息

Mitrovic M, Schildknecht E G, Maestrone G, Luther H G

出版信息

Avian Dis. 1980 Apr-Jun;24(2):302-8.

PMID:7002146
Abstract

In a series of controlled battery trials, Rofenaid (at doses ranging from 0.02 to 0.12% active drug in feed) was administered to ducklings infected experimentally with Pasteurella anatipestifer and Escherichia coli strains. Against P. anatipestifer, Rofenaid at 0.02 to 0.12% levels in feed either prevented or reduced mortality, gross lesions, and bacterial isolations. Furthermore, the weight gain and feed conversion of infected Rofenaid-medicated ducklings were superior to those of uninfected unmedicated controls in two out of three trials. Against E. coli, Rofenaid at 0.02 to 0.08% levels in feed either prevented or reduced mortality, gross lesions, and bacterial isolations. Weight gain and feed conversion of infected Rofenaid-medicated ducklings were also superior to those of uninfected unmedicated controls in two out of three trials. It appears that Rofenaid, at a 0.02-0.08% level, controls infections in ducklings caused by P. anatipestifer and E. coli strains sensitive to this compound.

摘要

在一系列对照试验中,将Rofenaid(饲料中活性药物剂量为0.02%至0.12%)给予经实验感染鸭疫里默氏杆菌和大肠杆菌菌株的雏鸭。对于鸭疫里默氏杆菌,饲料中0.02%至0.12%水平的Rofenaid可预防或降低死亡率、肉眼可见病变及细菌分离率。此外,在三项试验中的两项试验里,感染Rofenaid药物的雏鸭的体重增加和饲料转化率优于未感染未用药的对照组。对于大肠杆菌,饲料中0.02%至0.08%水平的Rofenaid可预防或降低死亡率、肉眼可见病变及细菌分离率。在三项试验中的两项试验里,感染Rofenaid药物的雏鸭的体重增加和饲料转化率也优于未感染未用药的对照组。看来,0.02%至0.08%水平的Rofenaid可控制雏鸭中由对该化合物敏感的鸭疫里默氏杆菌和大肠杆菌菌株引起的感染。

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