Sandhu T S, Layton H W
Avian Dis. 1985 Jan-Mar;29(1):128-35.
A combination Escherichia coli serotype O78 and Pasteurella anatipestifer bacterin was developed and tested in white pekin ducks in laboratory and field trials. Inoculations with bacterin at 2 and 3 weeks of age provided significant protection against challenge with virulent E. coli O78 and Pasteurella anatipestifer serotypes 1, 2, and 5. No significant cross-protection was observed against heterologous E. coli serotypes, although there was a slight reduction in mortality in ducklings challenged with E. coli serotypes O2a and O119. In field trials, the E. coli-P. anatipestifer bacterin produced significant reduction of mortality in commercial white pekin ducks compared with P. anatipestifer bacterin.
一种大肠杆菌O78血清型和鸭疫里默氏杆菌联合疫苗已研制成功，并在实验室和田间试验中对北京鸭进行了测试。在2周龄和3周龄时接种该疫苗，可有效抵御强毒大肠杆菌O78以及鸭疫里默氏杆菌1型、2型和5型血清型的攻击。对于异源大肠杆菌血清型，未观察到显著的交叉保护作用，不过，在用O2a和O119大肠杆菌血清型攻击的雏鸭中，死亡率略有降低。在田间试验中，与鸭疫里默氏杆菌疫苗相比，大肠杆菌-鸭疫里默氏杆菌联合疫苗可显著降低商品北京鸭的死亡率。
