Manousos O N, Zografos A, Nicolaou A, Scandalis N, Kalogerakou-Ioannidi E
J Int Med Res. 1978;6(5):381-3. doi: 10.1177/030006057800600505.
The results of a double-blind study comparing oral cimetidine with placebo in the short-term treatment of endoscopically proven gastric and duodenal ulceration are presented. Cimetidine was used at a dosage of one gram per day and treatment continued over a period of 4 weeks. Greek patients' tolerance of the drug has been recorded. The outcome of treatment was significantly better for the group of patients who received cimetidine treatment.
本文呈现了一项双盲研究的结果,该研究比较了口服西咪替丁与安慰剂在短期内治疗经内镜证实的胃溃疡和十二指肠溃疡的效果。西咪替丁的使用剂量为每日1克,治疗持续4周。记录了希腊患者对该药物的耐受性。接受西咪替丁治疗的患者组治疗结果明显更好。