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Sxr雄性小鼠的减数分裂:II. 性反转(Sxr)小鼠中Y染色体与常染色体发生重排的细胞学证据的进一步缺失

Meiosis in Sxr male mice: II. Further absence of cytological evidence for a Y-autosome rearrangement in sex-reversed (Sxr) mice.

作者信息

Evans E P, Burtenshaw M D, Brown B B

出版信息

Chromosoma. 1980;81(1):19-26. doi: 10.1007/BF00292420.

DOI:10.1007/BF00292420
PMID:7002501
Abstract

If the sex-reversal factor (Sxr) in mice is represented by a segment of the Y chromosome translocated on to an autosome, this segment might be expected to show some evidence of attempted pairing with the normal Y chromosome at the first meiotic division. Our failure to find such evidence in a light microscope study of the silver-stained pachytene spermatocytes from Sxr/4, XY males further supports existing cytological information that the factor is more likely to be represented by an autosomal dominant gene mutation.

摘要

如果小鼠中的性别反转因子(Sxr)由一段易位到常染色体上的Y染色体片段所代表,那么在第一次减数分裂时,这段片段可能会显示出与正常Y染色体试图配对的一些证据。我们在对Sxr/4、XY雄性小鼠的银染粗线期精母细胞进行光学显微镜研究时未能找到此类证据,这进一步支持了现有的细胞学信息,即该因子更可能由常染色体显性基因突变所代表。

相似文献

1
Meiosis in Sxr male mice: II. Further absence of cytological evidence for a Y-autosome rearrangement in sex-reversed (Sxr) mice.Sxr雄性小鼠的减数分裂:II. 性反转(Sxr)小鼠中Y染色体与常染色体发生重排的细胞学证据的进一步缺失
Chromosoma. 1980;81(1):19-26. doi: 10.1007/BF00292420.
2
Meiosis in Sxr male mice. I. Does a Y-autosome rearrangement exist in sex-reversed (Sxr) mice?Sxr雄性小鼠的减数分裂。I. 性反转(Sxr)小鼠中是否存在Y-常染色体重排?
Chromosoma. 1980;81(1):9-17. doi: 10.1007/BF00292419.
3
Meiotic studies in mice carrying the sex reversal (Sxr) factor.对携带性反转(Sxr)因子的小鼠进行的减数分裂研究。
Cytogenet Cell Genet. 1978;21(1-2):11-8. doi: 10.1159/000130874.
4
Serological and cytological evidence for increased Y-chromosome related material in Sxr,XY (sex-reversed carrier, male) mice.Sxr、XY(性反转携带者,雄性)小鼠中Y染色体相关物质增加的血清学和细胞学证据。
J Reprod Immunol. 1982 Aug;4(4):191-205. doi: 10.1016/0165-0378(82)90026-2.
5
Univalent sex chromosomes in spermatocytes of Sxr-carrying mice.携带Sxr的小鼠精母细胞中的单价性染色体。
Chromosoma. 1988;97(2):145-53. doi: 10.1007/BF00327371.
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Cytological evidence that the Sxr fragment of XY,Sxr mice pairs homologously at meiotic prophase with the proximal testis-determining region.细胞学证据表明,XY,Sxr小鼠的Sxr片段在减数分裂前期与近端睾丸决定区域同源配对。
Chromosoma. 1987;95(5):345-9. doi: 10.1007/BF00293181.
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Illegitimate pairing of the X and Y chromosomes in Sxr mice.Sxr小鼠中X和Y染色体的异常配对。
Genet Res. 1990 Oct-Dec;56(2-3):121-8. doi: 10.1017/s0016672300035199.
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XY pair associates with the synaptonemal complex of autosomal male-sterile translocations in pachytene spermatocytes of the mouse (Mus musculus).XY 配对与小鼠(小家鼠)粗线期精母细胞中常染色体雄性不育易位的联会复合体相关。
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Side-by-side pairing of the XY bivalent in spermatocytes and the ubiquity of the H-Y locus.精母细胞中XY二价体的并排配对以及H-Y基因座的普遍性。
Arch Androl. 1979 Mar;2(2):101-7. doi: 10.3109/01485017908987300.
10
Spermatogenesis in XO,Sxr mice: role of the Y chromosome.XO、Sxr 小鼠的精子发生:Y 染色体的作用
J Exp Zool. 1990 Oct;256(1):92-105. doi: 10.1002/jez.1402560112.

引用本文的文献

1
Conserved repeated DNA sequences in vertebrate sex chromosomes.脊椎动物性染色体中的保守重复DNA序列。
Hum Genet. 1981;58(1):46-53. doi: 10.1007/BF00284148.
2
Meiosis in Sxr male mice. I. Does a Y-autosome rearrangement exist in sex-reversed (Sxr) mice?Sxr雄性小鼠的减数分裂。I. 性反转(Sxr)小鼠中是否存在Y-常染色体重排?
Chromosoma. 1980;81(1):9-17. doi: 10.1007/BF00292419.
3
Genetic control of H-Y synthesis. A hypothesis.H-Y抗原合成的遗传控制。一种假说。

本文引用的文献

1
Cytological study of an X-autosome translocation in Mus musculus.小家鼠X-常染色体易位的细胞学研究。
Cytogenetics. 1962;1:129-40.
2
The sensitivity of various germ-cell stages of the male mouse to radiation induced translocations.雄性小鼠不同生殖细胞阶段对辐射诱导易位的敏感性。
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3
Sex-reversed mice: XX and XO males.性反转小鼠:XX和XO雄性小鼠。
Hum Genet. 1982;61(1):1-2. doi: 10.1007/BF00291320.
4
Cytological evidence that the Sxr fragment of XY,Sxr mice pairs homologously at meiotic prophase with the proximal testis-determining region.细胞学证据表明,XY,Sxr小鼠的Sxr片段在减数分裂前期与近端睾丸决定区域同源配对。
Chromosoma. 1987;95(5):345-9. doi: 10.1007/BF00293181.
5
A tissue-specific fragile site associated with the sex reversed (Sxr) mutation in the mouse.与小鼠性反转(Sxr)突变相关的组织特异性脆性位点。
Chromosoma. 1987;96(1):67-71. doi: 10.1007/BF00285886.
6
Univalent sex chromosomes in spermatocytes of Sxr-carrying mice.携带Sxr的小鼠精母细胞中的单价性染色体。
Chromosoma. 1988;97(2):145-53. doi: 10.1007/BF00327371.
7
Sex chromosome pairing patterns in male mice of novel Sxr genotypes.新型Sxr基因型雄性小鼠的性染色体配对模式。
Chromosoma. 1989 Mar;97(5):390-5. doi: 10.1007/BF00292766.
Cytogenetics. 1971;10(5):318-37. doi: 10.1159/000130151.
4
The induction of translocations in mouse spermatozoa. I. Kinetics of dose response with acute x-irradiation.小鼠精子中易位的诱导。I. 急性X射线照射的剂量反应动力学。
Mutat Res. 1974 Feb;22(2):157-74. doi: 10.1016/0027-5107(74)90096-7.
5
Translocations, the predominant cause of total sterility in sons of mice treated with mutagens.易位是用诱变剂处理过的小鼠雄性后代完全不育的主要原因。
Genetics. 1974 Jan;76(1):73-91. doi: 10.1093/genetics/76.1.73.
6
Cytological detection of the c-25H deletion involving the albino (c) locus on chromosome 7 in the mouse.小鼠7号染色体上涉及白化(c)位点的c-25H缺失的细胞学检测。
Genetics. 1974 Nov;78(3):905-10. doi: 10.1093/genetics/78.3.905.
7
Cytological observations of deletions in pachytene stages of oogenesis and spermatogenesis in the mouse.小鼠卵子发生和精子发生粗线期缺失的细胞学观察。
Chromosoma. 1976 Nov 29;58(4):377-86. doi: 10.1007/BF00292845.
8
Extensive pairing of the XY bivalent in mouse spermatocytes as visualized by whole-mount electron microscopy.通过整装电子显微镜观察到的小鼠精母细胞中XY二价体的广泛配对。
J Cell Sci. 1977 Jun;25:1-15. doi: 10.1242/jcs.25.1.1.
9
Mouse chromosome translocations: visualization and analysis by electron microscopy of the synaptonemal complex.小鼠染色体易位:通过联会复合体的电子显微镜观察与分析
Science. 1977 May 20;196(4292):892-4. doi: 10.1126/science.870966.
10
Synaptonemal complex karyotyping in spermatocytes of the Chinese hamster (Cricetulus griseus). I. Morphology of the autosomal complement in spread preparations.中国仓鼠(黑线仓鼠)精母细胞的联会复合体核型分析。I. 铺展制片中常染色体组的形态学
Chromosoma. 1977 Mar 16;60(2):99-125. doi: 10.1007/BF00288459.