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Sxr雄性小鼠的减数分裂。I. 性反转(Sxr)小鼠中是否存在Y-常染色体重排?

Meiosis in Sxr male mice. I. Does a Y-autosome rearrangement exist in sex-reversed (Sxr) mice?

作者信息

Chandley A C, Fletcher J M

出版信息

Chromosoma. 1980;81(1):9-17. doi: 10.1007/BF00292419.

Abstract

Cytological evidence for the existence of a Y-autosomal rearrangement in meiotic cells of Sxr mice has been sought. At peachytene, in silver-stained light microscope spread preparations of XY, Sxr/+ and XO, Sxr/+ spermatocytes, evidence for pairing or association between a possible Y-bearing segment of a specific autosome and a sex chromosome could not, however, be found. Such sex chromosome-autosome associations as were seen were non-specific in nature, and occurred no more often in Sxr mice than in controls.

摘要

人们一直在寻找细胞学证据,以证明Sxr小鼠减数分裂细胞中存在Y染色体与常染色体的重排。然而,在粗线期,对XY、Sxr/+和XO、Sxr/+精母细胞进行银染光学显微镜铺片制备后,未发现特定常染色体的可能携带Y染色体的片段与性染色体之间配对或关联的证据。所观察到的这种性染色体与常染色体的关联本质上是非特异性的,在Sxr小鼠中出现的频率并不比对照组高。

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